Synthetic cfDNA
for NIPT Research
Generate unlimited, biologically accurate cell-free DNA data for algorithm development, validation, and research.
Why Synthetic
Real cfDNA is
scarce, sensitive,
and expensive.
Synthetic cfDNA removes the bottleneck. Generate exactly the data you need, when you need it, with perfect ground truth labels.
Unlimited Scale
Generate millions of samples with exact specifications. No consent barriers, no data sharing agreements, no waiting.
From 1 to 1 million samplesPerfect Labels
Every sample comes with ground truth. Know exactly what condition is present at what fetal fraction.
100% label accuracyRare Conditions
Generate trisomies, microdeletions, and sex chromosome aneuploidies on demand. Test the edge cases.
54 conditions availablePrivacy Safe
Synthetic data contains no patient information. Share freely, publish openly, collaborate globally.
Zero patient dataTechnology
How It Works
Our autoregressive transformer (AR v15) generates biologically coherent cfDNA sequences that pass clinical validation pipelines.
Learn
AR v15 model trained on real cfDNA captures fragment patterns, GC bias, and biological signatures.
Condition
Specify fetal fraction (2-25%), karyotype, and chromosome composition for each sample.
Generate
Autoregressive transformer generates sequences token-by-token, maintaining biological coherence.
Validate
4-level validation ensures distributional accuracy, z-score detectability, and downstream utility.
Validation
Clinically Validated
Our synthetic cfDNA passes z-score detection with clinical-grade sensitivity. The 4-level validation framework ensures both statistical accuracy and biological functionality.
View full validation reportApplications
What You Can Build
Algorithm Development
Train and validate NIPT detection algorithms with unlimited labelled data.
Method Validation
Test sensitivity at different fetal fractions and read depths against known ground truth.
ML Augmentation
Augment limited real data with synthetic samples. +10% AUC improvement demonstrated.
Rare Condition Testing
Generate microdeletions and SCAs that are impossible to collect at scale.
Privacy-Safe Research
Conduct research without patient data concerns. Share datasets openly.
Benchmark Creation
Create standardised benchmarks for comparing NIPT methods across laboratories.
Roadmap
What's Next
We're continuously expanding our synthetic data capabilities.
Ready to Get Started?
Contact us to discuss your synthetic cfDNA needs. Whether you need a standard dataset or custom generation, we'll help you find the right solution.