Platform How It Works Conditions Evidence Request Demo
Introducing the cfDNA Foundation Model

Transforming Prenatal Testing Through AI

Every year, 350,000 families wait weeks for prenatal test results that never arrive. Our AI-enhanced platform reduces test failures by 50-70%, enabling earlier answers and greater peace of mind.

0 -70%
Fewer Failures
0 M+
Samples Generated
0 weeks
Earlier Detection

The Future of
Prenatal Testing

Our AI-enhanced platform addresses the fundamental limitations of current NIPT technology, enabling earlier detection and dramatically reducing test failures.

01

Ultra-Low Foetal Fraction Analysis

Reliable detection at 1-2% foetal fractions versus the current 4%+ requirement. This breakthrough enables testing from 6-7 weeks gestation rather than 10+ weeks.

50-70% reduction in test failures
02

AI Foundation Model

State-of-the-art foundation model trained on unlimited synthetic data, enabling pattern recognition across 100-1000x larger datasets than any real-world collection.

10M+ synthetic samples for training
03

Earlier Detection Window

Results available 2-3 weeks earlier than current technology. Fewer repeat tests, earlier answers, and reduced anxiety for families during critical decision-making periods.

Testing from 7-8 weeks vs 10+ weeks
04

Population-Specific Equity

Actively addressing disparities in prenatal testing. Support for multiple ancestries including European, African, East Asian, South Asian, and Admixed American populations.

Equitable outcomes across all populations
05

Clinically Validated

Rigorous 4-level validation framework ensuring biological accuracy. All performance metrics validated against real clinical NIPT datasets.

99.9% sensitivity, 99% specificity
06

Privacy Preserving

Generate unlimited biologically accurate synthetic data without accessing sensitive patient information. Perfect for validation, development, and global deployment.

Zero patient data exposure

Two Products, One Mission

Our platform combines synthetic data generation with AI foundation models to transform prenatal testing. Here's how the technology works together.

Product 1

Synthetic cfDNA Generation

Our conditional diffusion model generates unlimited, biologically accurate synthetic cfDNA data at scale—enabling training datasets 100-1000x larger than any real-world collection whilst maintaining perfect ground truth labels.

01

Feature Extraction

Extract comprehensive features from real cfDNA: fragment lengths, GC content, positional biases, end motifs, and methylation patterns across diverse populations.

ATCG GCTA TAGC
02

Diffusion Model Training

Train the conditional diffusion model on extracted features. The U-Net learns to denoise samples conditioned on foetal fraction, karyotype, and clinical metadata.

03

Iterative Denoising

Starting from pure noise, the model iteratively refines samples through learned denoising steps, gradually revealing realistic cfDNA patterns with perfect ground truth labels.

04

Unlimited Synthetic Data

Generate unlimited synthetic cfDNA samples with specified conditions. Each sample maintains statistical properties matching real clinical data—enabling research and validation at unprecedented scale.

Product 2

cfDNA Foundation Model

Trained on unlimited synthetic data, our foundation model achieves breakthrough performance in prenatal testing—detecting genetic conditions at foetal fractions as low as 1-2% versus the current 4%+ requirement.

Earlier Detection

Testing from 7-8 weeks vs current 10+ weeks

Fewer Failures

50-70% reduction in test failures

Lower Thresholds

Reliable at 1-2% vs 4%+ foetal fraction

Detect 50+ Conditions

Our platform supports detection of a comprehensive range of chromosomal abnormalities and monogenic disorders—with synthetic data generation enabling validation for even the rarest conditions.

Aneuploidies

7 conditions
  • T21Trisomy 21 (Down Syndrome)
  • T18Trisomy 18 (Edwards Syndrome)
  • T13Trisomy 13 (Patau Syndrome)
  • 45,XMonosomy X (Turner Syndrome)
  • 47,XXYKlinefelter Syndrome
  • 47,XXXTriple X Syndrome
  • 47,XYYXYY Syndrome

Microdeletions

13 conditions
  • 22q11.2DiGeorge Syndrome
  • 5p-Cri-du-Chat Syndrome
  • 15q11Prader-Willi Syndrome
  • 15q11Angelman Syndrome
  • 1p361p36 Deletion Syndrome
  • 4p-Wolf-Hirschhorn Syndrome
  • +7 more microdeletions

Monogenic Disorders

30+ conditions
  • CFTRCystic Fibrosis
  • SMN1Spinal Muscular Atrophy
  • FMR1Fragile X Syndrome
  • DMDDuchenne Muscular Dystrophy
  • HBBSickle Cell Disease
  • F8/F9Hemophilia A/B
  • +24 more disorders

All conditions include accurate chromosomal dosage effects, proper foetal fraction integration, and validated Z-score detection across diverse populations.

Rigorous Validation

Our platform undergoes a 4-level validation framework ensuring biological accuracy and clinical performance across all use cases.

Metric
Current NIPT
Our Platform
Foetal Fraction Threshold
4%+
1-2%
Testing Window
10+ weeks
6-7 weeks
Test Failure Rate
3-8%
0.5-2%
Repeat Test Rate
5-10%
1-3%
0 .9% Sensitivity
Trisomy 21 Detection 99.9%
Sensitivity: 99.9% Specificity: 99.9%
Trisomy 18 Detection 99.7%
Sensitivity: 99.7% Specificity: 99.9%
Trisomy 13 Detection 99.5%
Sensitivity: 99.5% Specificity: 99.9%
Sex Chromosome Aneuploidies 98%+
Sensitivity: 98%+ Specificity: 99%+

4-Level Validation Framework

1 Statistical Distribution
2 Biological Accuracy
3 Clinical Performance
4 Population Equity

Built for Clinical Performance

Synthetic Data Generation

Model Type Conditional DDPM
Backbone U-Net + Attention
Foetal Fraction Range 1-20% configurable
Samples Generated 10M+ validated

Foundation Model

Detection Threshold 1-2% foetal fraction
Sensitivity 99.9% (T21)
Specificity 99.9%
Failure Reduction 50-70%

Population Coverage

Ancestries 5 populations
Conditions 50+ supported
Reference GRCh38
Validation 4-level framework

Clinical Impact

Real-world benefits for patients and healthcare providers

2-3 weeks
Earlier results for families
350,000
Fewer failed tests annually
5 populations
Equitable coverage globally
Zero
Patient data exposure

Transform Your
Prenatal Testing

Whether you're a healthcare provider, researcher, or diagnostic laboratory, we can help you reduce test failures and enable earlier detection.

For Healthcare Providers

Offer your patients earlier, more reliable prenatal testing with fewer failures and repeat tests.

Learn More

For Laboratories

Integrate our foundation model to dramatically reduce test failures and improve turnaround times.

Contact Sales