Available Now
How we
tested it
The one validation result we claim: a classifier trained only on our synthetic data reached AUC 0.87 for T21 on one published dataset (Lun et al. 2014: 26 unique samples, 6 T21 and 20 euploid; p = 0.002). Labelled FASTQ for caller testing.
Train Synthetic, Test Real
Detecting Real T21 With Synthetic Training Data
A classifier trained only on our synthetic data reached AUC 0.87 for T21 on one published dataset (Lun et al. 2014: 26 unique samples, 6 T21 and 20 euploid; p = 0.002).
Data Products
Choose Your Data Package
Self-serve aneuploidy starter pack at $399, deeper four-file packs, or catalogue/generate on the dashboard.
Aneuploidy starter pack
T21 + T18 + T13 + matched euploid as one checkout
$399
- 4M PE each at 8% FF
- T21 is QC-verified. T18 and T13 ship once QC passes.
- Deeper packs $200–$800 for the same four files
- Other conditions available via catalogue/generate, not the homepage SKU
- Delivered as paired-end FASTQ
- Pack quantity 1 — not a 25-sample minimum
Catalogue & generate
Conditions beyond the starter pack, self-serve on the dashboard
Self-serve
- Same generation path as the starter pack
- Catalogue reuse or generate a new file
- Questions: kyle@eabhaseq.com
Validation
How we tested it
One result, stated with the experiment that produced it.
Train Synthetic, Test Real
A classifier trained only on our synthetic data reached AUC 0.87 for T21 on one published dataset (Lun et al. 2014: 26 unique samples, 6 T21 and 20 euploid; p = 0.002).
Applications
What You Can Build
Algorithm Development
Train and validate NIPT detection algorithms with labelled synthetic data. Test edge cases like low fetal fraction that are rare in real datasets.
Pipeline verification
Drop FASTQ into the analysis step. This does not exercise extraction or the sequencer.
Privacy-Compliant Research
Conduct research without patient data concerns. Synthetic data contains no identifiable information.
Education & Training
Train clinical scientists and bioinformaticians with realistic data. Perfect for courses and workshops.
Benchmark Creation
Create standardised benchmarks with known ground truth for comparing NIPT methods across laboratories.
Specifications
What's Included
| Parameter | Standard Dataset | Custom Generation |
|---|---|---|
| Fragments per sample | 4M (starter) | 4M–32M |
| Fragment length range | 50-250 bp | 50-250 bp |
| Fetal fraction | 8% default | 1% - 25% |
| Conditions | T21, T18, T13 + euploid controls | See the conditions page for what is currently available |
| Output format | paired-end FASTQ | paired-end FASTQ |
| Minimum order | 1 pack | 1 sample |
| Metadata | JSON per sample (FF, condition, params) | Full provenance tracking |
| Ground truth labels | Yes | Yes |
| Delivery | Secure download link | Secure download |
Order the files, or start with the free sample
Self-serve $399 starter pack. Catalogue and generate on the dashboard.